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butabarbital will minimize the level or outcome of nitrendipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.butabarbital will lessen the level or outcome of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar.As well as its required results, a medicin